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More In Other October 26, Clinical pharmacology of organic nitrates. Nitroglycerin works to dilate blood vessels, increasing blood flow to injured tissues. That same kind of increased blood flow also occurs in the head and brain, which can cause headaches. Headaches are generally mild, last less than 30 minutes, and resolve after two weeks of nitroglycerin use. This compared to only 64 percent of patients healed two months after botulinum toxin injections.
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0.4% nitroglycerin ointment : in the treatment of chronic anal fissure pain.

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